Vitamins and SupplementsDiseaseExpert Corner

Vitamin B12 Deficiency: A Knowledgeable Report

Vitamin B12 is a nutrient that aids in the health of your body’s blood and nerve cells, as well as the production of DNA, which is the genetic material found in all of your cells. Vitamin B12 also aids in the prevention of megaloblastic anemia, a blood disorder that causes fatigue and weakness. An involuntary twitch could be caused by a vitamin deficiency.

Vitamin B12 deficiency can cause twitching around the eyes.

The twitching, medically known as myokymia, can be caused by a variety of factors, the most prevalent of which being stress and weariness.

There is another factor that could cause intermittent eye twitching: a vitamin B12 deficit.

It is an involuntary, spontaneous trembling of a few muscles or bundles within a muscle that is not enough to move a joint.

It’s when the eyelid muscles, mainly the orbicularis oculi, contract spontaneously. It is frequently unilateral (affecting only one eye) and affects the lower eyelid rather than the upper.

Stress, weariness, allergies, or dry eyes, among other factors, can cause the condition.

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The Condition Is Usually Harmless And Self-Limiting

Deficiency Of B12 Levels Might Also Cause Following Symptoms:

  • Weakness, fatigue, or a feeling of being light-headed
  • Shortness of breath and heart palpitations
  • Pale skin
  • A well-knit tongue
  • Constipation, diarrhea, loss of appetite, or gas are all symptoms of a digestive problem
  • Nerve issues such as numbness or tingling, muscle weakness, and walking difficulties
  • There is a loss of vision or Myokymia 

A vitamin B12 imbalance can lead fatigue, weakness, numbness and tingling in the fingers and toes, and other symptoms.

Older persons who don’t make enough hcl acid in their stomach to absorb the vitamin naturally via diet are at risk of vitamin B12 deficiency. Due to poor absorption, those with digestive illnesses like Crohn’s disease and celiac disease, and those who have had weight loss surgery/gastrointestinal surgery, may be insufficient in B12.

Health Benefits Of Vitamin B12

Vitamin B12 offers numerous health advantages. It has been shown to improve memory, mood, nervous system function, iron levels, heart health, hair, nails, and skin, among other things.

Blood Health

Vitamin B12 is essential for the body’s production of healthy red blood cells. When the body is weak in vitamin B12 or has insufficient levels of the vitamin, red blood cells grow incorrectly.

As a result, red blood cells grow in size and become irregular in shape. This keeps them from getting into the bloodstream from the bone marrow.

Because your body doesn’t have enough red blood cells to deliver oxygen to your organs, anemia can cause weakness, exhaustion, and other symptoms over time.

Brain Health

Vitamin B12 has been shown in studies to aid brain and nervous system function, memory, mood, as well as depression. According to research, people with depression, both patients as well as the general community, have inadequate folate as well as vitamin B12. 3 Vitamin B12 insufficiency has also been linked to poor memory in other research.

Skin Health

Vitamin B12 is well-known for its beneficial effects on the skin, hair, and nails. Discolored areas, skin hyperpigmentation, vitiligo, and impaired hair development are all symptoms of vitamin deficiency.

Heart Health

Vitamin B12 has been shown in studies to lower homocysteine levels in the blood. This amino acid has been linked to a rise in heart disease. People with moderately elevated homocysteine levels had a higher risk of heart attack and stroke, according to research.


Vitamin B12 is obtained through supplements and meals. Vitamin B 12 is found naturally in the following foods:

  • Sardines
  • Trout
  • Chicken breast
  • Clam
  • Salmon
  • Eggs
  • Ham
  • Tuna
  • Milk
  • Lamb
  • Plain Greek yogurt
  • Fortified nutritional yeast

The amount needed to sustain a healthy haematological condition and serum Vitamin B12 levels was the key criterion utilized by the FNB to establish the RDAs for adults. The FNB set an AI for infants aged 0 to 12 months that is similar to the average vitamin B12 consumption in healthy, breastfed infants.

Recommended Dietary Allowances For Vitamin B12 

Birth to 6 months0.4 mcg0.4 mcg
7–12 months0.5 mcg0.5 mcg
1–3 years0.9 mcg0.9 mcg
4–8 years1.2 mcg1.2 mcg
9–13 years1.8 mcg1.8 mcg
14–18 years2.4 mcg2.4 mcg2.6 mcg2.8 mcg
19+ years2.4 mcg2.4 mcg2.6 mcg2.8 mcg

Doses Suggestions

Vitamin B12 is found in 2.4 micrograms per day in the recommended dietary limit. The usual range for picograms per millilitre (pg/ml) is 200 to 900.

A vitamin B12 deficiency is defined as a value of less than 200 pg/ml of vitamin B12. A blood test can be used to determine vitamin B12 levels by a medical expert.

Risks And Interactions

Although research has proven that taking vitamin B12 poses no risk, it is still a good idea to see your doctor before starting any vitamin, mineral, or supplement. A medical professional can best assess whether you have a need for it right now.

Vitamin B12 has been reported to interact with various medicines in studies. The following medicines are known to interfere with the body’s absorption of vitamin B12, as per National Institute of Health:

Chloromycetin (Chloramphenicol)

Some infections are treated with this antibiotic.

Proton Pump Inhibitors

These include Prilosec (omeprazole) and Prevacid, which are used to treat acid reflux as well as peptic ulcer disease (lansoprazole).

Histamine H2-Receptor Antagonists

Tagamet (cimetidine), Pepcid (famotidine), and Zantac are some of the medications used to treat peptic ulcer disease (ranitidine).


Insulin resistance and diabetes are treated with this medication.

Talk to your doctor or medical staff before taking vitamin B12 and inform them about any drugs, vitamins, or supplements you’re taking.


You may have blood tests to look for the following things to assist detect vitamin deficient anemias:

  • The amount of red blood cells and their appearance
  • Vitamin B-12 as well as folate levels in the blood
  • The presence of intrinsic factor antibodies, that indicates pernicious anemia.

Vitamin B12 Deficiency Treatment

Anemia caused by a vitamin deficiency is treated with doses of the vitamin in question. Vitamin B-12 is commonly given as an injection to treat pernicious anemia and may need to be taken on a regular basis for the rest of your life.

Vitamin B-12 is available in the following forms:

  • Injections into a muscle or beneath the surface of the skin
  • To be taken pills
  • A pill or liquid that dissolves beneath the tongue.
  • Sprays or gels for the nose
  • Medications to increase folate levels are normally taken as pills, although certain forms can be injected into a vein through a small, flexible tube (intravenously).


Vitamin B12 is a necessary component of the human diet. Many organs in the body rely on it for development and appropriate functioning. You should strive to get your daily vitamin B12 requirement from foods that naturally contain the vitamin. If you’re not sure if you’re receiving enough vitamin B12, talk to your doctor about obtaining a blood test, eating the right foods, and possibly supplementing your diet.

People May Ask

Is B12 Good For Hair Growth?

B12, often known as cobalamin, is one of these essential elements. B12 aids in the creation of oxygen-rich red blood cells, which nourish hair follicles, promoting healthy hair development.

Is It Safe To Take 1000 Micrograms Of B12 Every Day?

A daily dose of 1000 mcg of vitamin B12 is indicated to treat vitamin B12 insufficiency.

Is B12 Effective To Weight Loss?

Because of its potential to improve metabolism and offer long-lasting energy, B12 is frequently linked to weight loss.

How Long Does B12 Take To Take Effect?

It may take a few weeks for your vitamin B12 levels to improve and your symptoms to improve.

Which Fruit Is Rich In Vitamin B12?

Banana, Apples and Berries


The opinions presented in this article should not be regarded as a replacement for medical advice. For more information, please contact your treating physician.

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